Rated 4.9 out of 5 stars
152 Reviews

Prepare for a great night’s sleep with Duo tablets for relaxation and rest. We topped off our signature oral microbiome-balancing tablets with a perfectly portioned dose of melatonin (1.5mg), L-theanine (2.5mg), and lavender to regulate circadian rhythms, ease stress, and ready your system for nourishing rest.

Your subcription will include 1 glass printed bottle that holds 62 tablets + compostable refill pouches.

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Inside the tablet

1.5mg Melatonin
regulates circadian rhythms and sleep
2.5mg L-theanine
calms the nerves
nano-hydroxyapatite (nHa)
remineralizes teeth
xylitol (birch extract)
promotes saliva production
calcium carbonate
natural polish
sodium bicarbonate
natural polish
provides structure to tablets
xanthan gum
protects against dry mouth
magnesium stearate
vegetable-derived powder lubricant
hydrated silica
natural polish
cooling, soothing sensation
lavender, French vanilla, peppermint, spearmint, wintergreen
natural flavor
vitamin C, vitamin E
gum health
stevia leaf extract
cavity-fighting plant extract

How Duo supplements work

Our mouths absorb nutrients directly into the bloodstream. That’s the key to the efficient bio-availability of the vitamins and supplements in Duo, added for convenience and health.

  • absorbs while you brush
  • gentle, efficient digestion
  • rapid uptake
Standard Supplement Pills
  • uncomfortable to swallow
  • difficult gastrointestinal digestion
  • delayed delivery





Dentist Created







“What you brush 
with matters.”

Tooth enamel cannot repair itself from within, which means your toothpaste has an important job to do. We packed Duo with proven ingredients like nHa to remineralize teeth and promote vibrant oral health. Developed by dentists, better for everyone.

Image sign

Dr. Stevie Roberts, DMD

Dr. Robert Johnson, DMD, MD

Clean Ingredients

Restore and whiten enamel, soothe sensitivity, and balance the oral microbiome while preparing for deep, restful sleep.


A dentist-backed fluoride alternative that whitens and remineralizes enamel.

Melatonin (1.5mg) 

Regulates circadian rhythms and helps to initiate and maintain sleep without grogginess

L-theanine (2.5mg) 

Naturally occurring in green tea; improves cognitive performance without jitters

How to brush with Duo

Crush a tablet between your teeth

Wet your toothbrush

Brush to activate foam

Rinse and smile

Plastic-free made easy

Save up to 33% and lower your carbon footprint with subscription refills (in compostable pouches) delivered right on time.


Rated 4.9 out of 5 stars
Based on 152 reviews
152 reviews
  • NC
    Nancy C.
    Verified Buyer
    Original Compostable Refill
    Original Compostable Refill
    I recommend this product
    Rated 5 out of 5 stars
    4 days ago
    Love it

    Minty fresh

    No gross tube

    Cute little bottle

    Great check ups

  • JA
    Jaime A.
    Verified Buyer
    I recommend this product
    Rated 4 out of 5 stars
    4 weeks ago
    haven't used enough to say

    I have only used this once so far and the flavor is okay. I prefer the flavor of the original better cause of its minty ness.

  • JT
    Joseph T.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    1 month ago
    Great Way to End a Day

    This toothpaste has a lovely flavor and helps me relax after a long day.

  • MG
    Marie G.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    1 month ago
    Great alternative

    Great alternative to traditional toothpaste. Just the right amount of foam and minty fresh flavor. In fact I find that half a tablet is sufficient. I have sensitive teeth and this helps with that as well. Simple and effective ingredients. I do find them a bit pricy but I suppose you get what you pay for.

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