The Science of 

Mucosal Absorption

The highly absorbent tissues in your mouth deliver nutrients directly into the bloodstream.

Man in blue shirt holding toothbrush and duo bottle.
First, the problem ...

Many simply forget to buy or take their supplements, even the ones recommended to them (think of the vitamin D you only purchase when at the doctor’s office).

On top of that, pills have to be made with fillers, which can be hard on the stomach, and some key vitamins and supplements are difficult to absorb through the digestive system, including melatonin and vitamin B12.

Toothbrush and whitening toothpaste with bubbles in a modern, clean design.

Brushing as a solution

A team of doctors conducted a study that infused B12 in toothpaste. Eureka! The data confirmed that brushing with B12 infused toothpaste corrects the vitamin deficiency just as effectively as swallowing tablets.

Plus, there were none of the drawbacks or side effects that come with pills. Brushing, it turns out, is an incredibly efficient delivery mechanism for certain vitamins and supplements, including the ones in our tablets.

Person using toothpick from Duo bottle with a smile.

Why it works

The reason this works is thanks to a scientific process called mucosal absorption. The mouth is full of blood capillaries and absorbent tissue.

Certain vitamins and supplements pass through the mucosa into the bloodstream when they come into contact with the gums, inner cheeks, and thin membranes under your tongue.

Brown bottle labeled 'duo Whitening Toothpaste' with tablets and a toothbrush on a green background.

Better with Duo

The vitamins and supplements used in Duo are all scientifically proven to absorb through your oral membrane and into your bloodstream. 

That’s what’s happening as you brush with Duo! It’s why you feel the caffeine in Duo Energy almost right away, and why the melatonin in Duo Sleep is 10x more bioavailable a pill form.