Rated 4.9 out of 5 stars
159 Reviews

Brush your way to a better morning with Duo tablets for mood and metabolism support. We topped off our signature oral microbiome-balancing tablets with a perfectly portioned dose of caffeine (10mg), vitamin B12 (6mcg), and L-theanine (2.5mg) to invigorate your system. A feel-good start to the day.

Your subcription will include 1 glass printed bottle that holds 62 tablets + compostable refill pouches.

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Inside the tablet

10mg caffeine
cognitive performance
6mcg vitamin B12
DNA synthesis and cellular energy production
2.5mg L-theanine
calms the nerves
nano-hydroxyapatite (nHa)
remineralizes teeth
xylitol (birch extract)
promotes saliva production
calcium carbonate
natural polish
sodium bicarbonate
natural polish
provides structure to tablets
xanthan gum
protects against dry mouth
magnesium stearate
vegetable-derived powder lubricant
hydrated silica
natural polish
cooling, soothing sensation
peppermint, wintergreen, spearmint
natural flavor
cinnamon, chai
anti-inflammatory and antioxidant
vitamin C, vitamin E
gum health
stevia leaf extract
cavity-fighting plant extract

How Duo supplements work

Our mouths absorb nutrients directly into the bloodstream. That’s the key to the efficient bio-availability of the vitamins and supplements in Duo, added for convenience and health.

  • absorbs while you brush
  • gentle, efficient digestion
  • rapid uptake
Standard Supplement Pills
  • uncomfortable to swallow
  • difficult gastrointestinal digestion
  • delayed delivery





Dentist Created







“What you brush 
with matters.”

Tooth enamel cannot repair itself from within, which means your toothpaste has an important job to do. We packed Duo with proven ingredients like nHa to remineralize teeth and promote vibrant oral health. Developed by dentists, better for everyone.

Image sign

Dr. Stevie Roberts, DMD

Dr. Robert Johnson, DMD, MD

Clean Ingredients

Restore and whiten enamel, soothe sensitivity, and balance the oral microbiome with a gentle boost to start the day.


A dentist-backed fluoride alternative that whitens and remineralizes enamel.

Caffeine (10mg)

Increases mental alertness, cognitive performance, metabolism, and reaction time

Vitamins B12 (6mcg) 

Elevates mood and aids neurological function

L-theanine (2.5mg) 

Naturally occurring in green tea; improves cognitive performance without jitters

How to brush with Duo

Crush a tablet between your teeth

Wet your toothbrush

Brush to activate foam

Rinse and smile

Plastic-free made easy

Save up to 33% and lower your carbon footprint with subscription refills (in compostable pouches) delivered right on time.


Rated 4.9 out of 5 stars
Based on 159 reviews
159 reviews
  • C
    Energy Compostable Refill
    Energy Compostable Refill
    I recommend this product
    Rated 5 out of 5 stars
    4 minutes ago
    5 Stars

    I am so glad that Duo has refills available! I love the easy travel bottles and having refills available is so convenient. I have tried other toothpaste tabs but find Duo to be easier to chew. Also, they do not contain fluoride but still provide cavity protection !!

    Thank you, Duo ❤️

  • MS
    Melissa S.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9 hours ago
    Love it!

    These tablets are the best! The only thing I would like is to have refills with no new bottle.

  • SR
    Samantha R.
    Verified Buyer
    I recommend this product
    Rated 4 out of 5 stars
    17 hours ago
    Great product

    It made brushing my sensitive teeth easier and left my teeth feeling clean without pain.

  • SR
    Samantha R.
    Verified Buyer
    Original Compostable Refill
    Original Compostable Refill
    I recommend this product
    Rated 4 out of 5 stars
    17 hours ago
    Fresh clean feeling

    My first use and my teeth felt incredibly clean! I have already suggested this product to several people!

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