The Science

Duo 101

Developed with leading science and the best from nature, Duo is at the forefront of bridging oral health with systemic wellness.

Inside the Tablet

Formulated by co-founders Stevie Roberts, DMD and Robert Johnson DMD, MD with leading science and the best from nature, Duo improves dental, oral and systemic health.






nano-hydroxyapatite (nHa)

Nano-hydroxyapatite, or nHa, is the dentist-backed fluoride alternative in Duo that remineralizes enamel, removes plaque, whitens, and blocks sensitivity.

Xylitol & Xanthan gum

Promote saliva production, reduce biofilm, and slow the growth of disease-causing bad bacteria.

Hydrated silica, Calcium carbonate & Sodium bicarbonate

Balance PH, naturally polish, and whiten without damaging enamel.

Vitamins C & E

Synergistically support periodontal health and soothe and restore gums.

What you
will not find

Detergents like SLS used for foaming that cause dry mouth

Dyes like titanium dioxide to artificially make paste white

Fillers like glycerin made from animal fat for gunky texture

Chemicals that kill good bacteria and harm the oral microbiome

Plastics that end up in our landfills and oceans

Why nHa?

We use a dentist-backed fluoride alternative called nano-hydroxyapatite, which is clinically proven to be just as effective as fluoride- if not more so- at remineralizing teeth.


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The gateway to
systemic health

Science continues to uncover the depth and complexity of the connection between oral health and the health of all major systems in the body.

Duo is packed with science-backed ingredients that support and nourish your oral health, including the microbiome. This is key to reducing risk of oral and systemic disease and to improving overall health outcomes.

+ function

The vitamins and supplements added to our toothpaste tablets have high bioavailability and are efficiently absorbed as you brush (more on that below). We carefully selected each because of its health and functional benefits. 

The science behind mucosal absorption

Our mouths absorb nutrients directly into the bloodstream. That’s the key to the efficient bio-availability of the vitamins and supplements in Duo.