Sleep
Toothpaste

Toothpaste tablets featuring melatonin 

and a relaxing lavender mint flavor for

the perfect wind-down.

Learn more

4.9

176 Reviews

Sleep
Toothpaste

4.9

Toothpaste tablets featuring melatonin and a relaxing lavender mint flavor for the perfect wind-down.

Learn more

Man smiling, holding a toothbrush and a bottle of Duo dental product with a purple background.

Sleep Better:

How it Works

Your mouth is full of absorbent tissue that delivers the melatonin directly into your bloodstream while you brush - no swallowing needed.

Purple circle with a white crescent moon and star icon.

Interaction with oral receptors enhances effect by priming the brain to downshift your circadian rhythm.

Simple moon and star icon on a purple background.

10x the bioavailability of pill-based supplements, with none of the wait time.

Why Duo?

Better-for-you
toothpaste tablets

Whitens Naturally.

Without peroxides or
chemicals that strip enamel.

Hydrating Foam.

Free from SLS and drying
agents for fresher breath.

Vitamins & Supplements.

Absorbed as you brush for
oral and systemic health.

Decreases Sensitivity.

Core ingredients, like nHA, insulate nerves without numbing agents.

Travel-Ready.

TSA-compliant and mess-free convenience.

Vegan and Cruelty-Free

Clean ingredients with all-natural flavors for a feel-good routine.

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'

Why Duo?

Better-for-you toothpaste tablets

Whitens Naturally.

Without peroxides or chemicals that strip enamel.

Decreases Sensitivity

Core ingredients, like nHA, insulate nerves without numbing agents.

Hydrating Foam.

Free from SLS and drying agents for healthy balance.

Vitamins & Supplements.

Absorbed as you brush for oral and systemic health.

Travel-Ready

TSA-compliant and mess-free convenience.

Vegan and Cruelty-Free

Clean ingredients with all-natural flavors for a feel-good routine.

Hand holding a wooden toothbrush with a white pill on green bristles.

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
Hand holding a wooden toothbrush with a tablet on the bristles against a purple background.
Man smiling, holding a toothbrush and a bottle of Duo dental product with a purple background.

Sleep Better:

How it Works

Your mouth is full of absorbent tissue that delivers the melatonin directly into your bloodstream while you brush - no swallowing needed.

Purple circle with a white crescent moon and star icon.

Interaction with oral receptors enhances effect by priming the brain to downshift your circadian rhythm.

Simple moon and star icon on a purple background.

10x the bioavailability of pill-based supplements, with none of the wait time.

How to brush with Duo

1

Chew tablet
to break
down

2

Wet your toothbrush

3

Brush to activate
foam

4

Spit and
smile

Watch explainer with Dr. Stevie Roberts

Hand holding a wooden toothbrush with a tablet on pink bristles.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Sleep Well!

"Love, love, love this toothpaste experience. A super pleasant way to wind down the evening. Highly recommend!"

-Heather C.

4.9

176 Reviews

Best Toothpaste Ever!

"I’ve never tried a better toothpaste. Besides the fact that my teeth feel the most clean, I sleep so well. For someone with insomnia this is really just the best product on the market."

- Ayanna G.

Purchase One-Time or Subscribe

whitens naturally 

without bleaching

nano-hydroxyapatite

for remineralizing teeth

antioxidants

for gum health

melatonin (1.5mg)

promotes healthy sleep

L-theanine (2.5mg)

calms the nerves

vitamins absorbed

directly while brushing

Brown bottle of Duo Whitening Toothpaste tablets with immunity support, containing vitamin D and B12.Two jars and two packets of Duo whitening toothpaste tablets in Sleep and Original varieties.

1.5mg of melatonin || lavender mint

Sleep Whitening

Toothpaste Tablets

4.9

167 Reviews

Prepare for a great night’s sleep with Duo tablets for relaxation and rest. We topped off our signature oral microbiome-balancing tablets with a perfectly portioned dose of melatonin (1.5mg), L-theanine (2.5mg), and lavender to regulate circadian rhythms, ease stress, and ready your system for nourishing rest.

2 Months / 124 tablets - SAVE 20%

2 Months / 124 tablets - SAVE 20%

1 Bottle (62 tablets) 

1 Bottle (62 tablets) 

1 Bottle (62 tablets) 

One-Time Purchase

Monthly Delivery

***

Subscribe to

save up to 33%

$18.00

$12.00/month

Save 33%

$18.00

$12.00/month

Save 33%

$18.00

$12.00/month

Save 33%

*** Subscriptions include glass printed bottles of Sleep and Original (1 of each) that hold 62 tablets each along with refills that come in compostable pouches. 

+ 100% Guaranteed - return for full refund if not satisfied
+ Free shipping on all orders over $20

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Plastic free
for the planet

Duo is delivered in apothecary-grade, recyclable glass bottles. Subscription refills come in compostable pouches. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes
end up as trash
each year

A bottle of Duo Whitening Toothpaste tablets against a purple background.

Plastic free
for the planet

Duo is delivered in apothecary- grade, recyclable glass bottles. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes end up as trash each year

Reviews

4.9
Rated 4.9 out of 5 stars
Based on 187 reviews
187 reviews
  • MG
    Marie G.
    Verified Buyer
    Original Compostable Refill
    Reviewing
    Original Compostable Refill
    I recommend this product
    Rated 5 out of 5 stars
    28 minutes ago
    Great toothpaste

    Convenient and easy. Toothpaste option without the ick. Taste great and helps sensitivity. We find that half a tablet works well for us.

  • BC
    Bob C.
    Verified Buyer
    Original Compostable Refill
    Reviewing
    Original Compostable Refill
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Good for travel

    Duo is my goto for travel. Small bottle holds a month supply. No spills, no messy paste, easy to use in any hotel bathroom.

  • SH
    Sue-Simone H.
    Verified Buyer
    Original
    Reviewing
    Original
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Amazing

    How does such a little pill produce such luxurious foam? Duo makes my whole mouth feel pampered, so couple that with its clean ingredients, and I've got a new favorite toothpaste.

  • MC
    Michael C.
    Verified Buyer
    Sleep Compostable Refill
    Reviewing
    Sleep Compostable Refill
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Another keeper!

    I knew I wanted to switch from my regular "tube" toothpaste. Once I read into Duo's nHa formula and supplement-based tablets, I'm glad I went for it! Glad to be a subscriber today!

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