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Immunity
Toothpaste
4.9
Toothpaste tablets featuring your daily dose of vitamins D3 + B12
for better oral and systemic health.
Absorbed as you brush. No need to swallow.
Learn more
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Immunity
Toothpaste
Toothpaste tablets featuring your daily dose of
vitamins D3 + B12
for better oral and systemic health.
Absorbed as you brush. No need to swallow.
Learn more
4.9
245 Reviews
VEGAN
NON-TOXIC
SLS-FREE
DENTIST-CREATED
CRUELTY-FREE
FLUORIDE-FREE
PLASTIC-FREE
MADE IN U.S.
Five Reasons to Switch to Duo
1. Developed by dentists to optimize oral health
Co-founders Dr. Stevie Roberts and Dr. Robert Johnson formulated Duo toothpaste tablets to leverage the latest science for maximum oral and whole-body health. Duo uses all natural ingredients to clean and protect your teeth and gums, including nano-hydroxyapatite for remineralization and antioxidants for overall oral health. Drs. Roberts and Johnson also realized that with a more fun brushing experience, their patients would brush more often. So they designed Duo with great natural flavors and hydrating foaming action to get their patients excited to brush twice a day (or more!).
2. Nano-hydroxyapatite for natural remineralization and whitening
Hydroxyapatite is the primary mineral in your enamel that makes your teeth strong, and nano-hydroxyapatite (nHa) is a microscopic derivative of that mineral. nHa in toothpaste has proven to be highly effective at remineralizing teeth by naturally bonding with your enamel and dentin, reinforcing your teeth’s existing structure. And because hydroxyapatite is what makes your teeth white, nHa naturally whitens your teeth at the source!
3. Glass bottles and compostable refill pouches make Duo the sustainable choice
Duo toothpaste tablets come in apothecary-grade glass bottles, and refills are available in compostable pouches. With 1.5 billion toothpaste tubes discarded every year, and each tube taking 500 years to biodegrade, that is a lot of single-use plastic stacking up in our landfills – not anymore with Duo!
4. Say goodbye to tooth sensitivity without relying on numbing agents
The nHa in Duo toothpastes tablets is a key ingredient to prevent tooth sensitivity. Most sensitivity is caused by exposed nerves in your teeth’s dentin pores, and nHa naturally fills in those pores. No exposed nerves means no more tooth sensitivity! And unlike other toothpaste brands, Duo gets rid of your sensitivity without having to resort to numbing agents. With Duo, you can take on the day with confidence and pain-free!
5. Vitamins and supplements that absorb while you brush – no swallowing needed
Duo utilizes the magic of mucosal absorption to deliver vitamins and supplements directly into your bloodstream while you brush. This works because your mouth is full of capillaries and absorbent tissue that absorb nutrients and bypass the complex filtration systems your body uses to process pill-based supplements. Mucosal absorption gets you your supplements faster, with higher bioavailability and better effectiveness. And because you’re already brushing anyway, Duo means one less thing to worry about. With Duo, you can get more of what you need, when you need it!
Co-founded by Dentists
![Smiling person in a white blazer standing by a floral arrangement.](https://cdn.shopify.com/s/files/1/0553/3233/9879/files/Rectangle_231_2fc2579e-7b8d-459b-b832-38a5be1b153d.png?v=1723057467)
Stevie A. Roberts,
DMD
Founder of the dental practice Dentiste Kirkland in Seattle, WA, Dr. Roberts co-founded Duo toothpaste to bring better, science-backed ingredients to toothpaste tablets that work.
![Smiling man wearing a white coat and tie with a gray background.](https://cdn.shopify.com/s/files/1/0553/3233/9879/files/Rectangle_232_f0c1be83-96bc-4ba3-b826-65d07d3127b2.png?v=1723057504)
Robert E. Johnson,
DMD, MD
A graduate of the Department of Oral and Maxillofacial Surgery at the University of Washington. Dr. Johnson co-founded Duo with a commitment to oral and whole-body health.
Trusted by the industry
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!['MyDental Advocate logo with a tooth graphic.'](https://cdn.shopify.com/s/files/1/0553/3233/9879/files/MyDentalAdvocatex3_42eb77c6-c61a-4f64-90cc-2704443483a4.png?v=1721967070)
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Standard
Toothpaste
Plastic-Free + Compostable Refills
Vitamins & Supplements
SLS-Free & NO Harsh Chemicals
Reduces Sensitivity Without Numbing Agents
How to Brush with Duo
![Man holding a toothbrush and a small bottle, wearing a blue shirt.](https://cdn.shopify.com/s/files/1/0553/3233/9879/files/Duo-Brand_Shoot-568_1.png?v=1732069428)
1
Grab a Duo tablet
![Man holds toothbrush and bottle, smiling with tablet in mouth.](https://cdn.shopify.com/s/files/1/0553/3233/9879/files/Duo-Brand_Shoot-575_1.png?v=1732070292)
2
Crush a tablet between your teeth
![Man in blue holding a duo flossing product, smiling and demonstrating use.](https://cdn.shopify.com/s/files/1/0553/3233/9879/files/Duo-Brand_Shoot-587_1.png?v=1732070322)
3
Brush to activate foam
![Smiling person in a blue shirt pointing towards the camera.](https://cdn.shopify.com/s/files/1/0553/3233/9879/files/Duo-Brand_Shoot-587_2.png?v=1732070346)
4
Spit and smile
Subscribe or Purchase One-Time
whitens naturally
without bleaching
nano-hydroxyapatite
for remineralizing teeth
antioxidants
for gum health
vitamin D3 (30mcg)
to bolster defenses
vitamin B12 (6mcg)
for mood support
vitamins absorbed
directly while brushing
![Brown bottle of Duo Whitening Toothpaste tablets with immunity support, containing vitamin D and B12.](https://cdn.shopify.com/s/files/1/0553/3233/9879/files/Immunityimmunity_bottle.png?v=1722198023)
![Duo Whitening Toothpaste pack and bottle for immunity with vitamins D and B12, 62 tablets.](https://cdn.shopify.com/s/files/1/0553/3233/9879/files/Immunityimmunity_bottle.jpg?v=1722641698)
vitamin D3 + vitamin B12
Sleep Whitening
Toothpaste Tablets
4.9
167 Reviews
Prepare for a great night’s sleep with Duo tablets for relaxation and rest. We topped off our signature oral microbiome-balancing tablets with a perfectly portioned dose of melatonin (1.5mg), L-theanine (2.5mg), and lavender to regulate circadian rhythms, ease stress, and ready your system for nourishing rest.
1 Bottle (62 tablets)
1 Bottle (62 tablets)
1 Bottle (62 tablets)