Immunity
Toothpaste

4.9

Toothpaste tablets featuring your daily dose of vitamins D3 + B12 
for better oral and systemic health.

Absorbed as you brush. No need to swallow.

Learn more

Immunity
Toothpaste

Toothpaste tablets featuring your daily dose of
vitamins D3 + B12 
for better oral and systemic health.

Absorbed as you brush. No need to swallow.

Learn more

4.9

245 Reviews

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Five Reasons to Switch to Duo

Co-founded by Dentists

Smiling person in a white blazer standing by a floral arrangement.

Stevie A. Roberts,

DMD

Founder of the dental practice Dentiste Kirkland in Seattle, WA, Dr. Roberts co-founded Duo toothpaste to bring better, science-backed ingredients to toothpaste tablets that work.

Smiling man wearing a white coat and tie with a gray background.

Robert E. Johnson,

DMD, MD

A graduate of the Department of Oral and Maxillofacial Surgery at the University of Washington. Dr. Johnson co-founded Duo with a commitment to oral and whole-body health.

How to Brush with Duo

Man holding a toothbrush and a small bottle, wearing a blue shirt.

1

Grab a Duo tablet

Man holds toothbrush and bottle, smiling with tablet in mouth.

2

Crush a tablet between your teeth

Man in blue holding a duo flossing product, smiling and demonstrating use.

3

Brush to activate foam

Smiling person in a blue shirt pointing towards the camera.

4

Spit and smile

4.9

254 Reviews

Duo Immunity

Duo Whitening Toothpaste pack and bottle for immunity with vitamins D and B12, 62 tablets.
Whitening Toothpaste Tablets

vitamin D3 (30mcg) + vitamin B12 (6mcg)

We topped off our original nHa whitening tablets with vitamin D3 and vitamin B12 to bolster the body’s defenses and lift mood. Absorbed into your bloodstream directly and efficiently as you brush. 

Subscribe and Save

SAVE 33%

4-month supply of 248 tablets

Glass printed bottle + compostable refill pouches

100% Guaranteed - return for full refund if not satisfied

Free shipping on all orders

One-time purchase

1 bottle of 62 tablets

Every 4 months - pause or cancel at anytime

whitens naturally 

without bleaching

nano-hydroxyapatite

for remineralizing teeth

antioxidants

for gum health

vitamin D3 (30mcg)

to bolster defenses

vitamin B12 (6mcg)

for mood support

vitamins absorbed

directly while brushing

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
'Black logo of the word 'duo' in lowercase letters.'

Standard
Toothpaste

Plastic-Free + Compostable Refills

Nano-Hydroxyapatite (Fluoride-Free) 

Vitamins & Supplements

SLS-Free & NO Harsh Chemicals

Hydrating Foam + Natural Flavors 

Reduces Sensitivity Without Numbing Agents

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Plastic free
for the planet

Duo is delivered in apothecary-grade, recyclable glass bottles. Subscription refills come in compostable pouches. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes
end up as trash
each year

Bottle labeled 'Duo Whitening Toothpaste' with tablets being poured from a packet.

Plastic free
for the planet

Duo is delivered in apothecary- grade, recyclable glass bottles. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes end up as trash each year

Reviews

4.8
Rated 4.8 out of 5 stars
Based on 294 reviews
294 reviews
  • CC
    Clydette C.
    Verified Buyer
    Reviewing
    Immunity
    I recommend this product
    Rated 5 out of 5 stars
    14 minutes ago
    I like it

    I like how clean my mouth feels after using it. It is easy to crunch a tablet and it will suds up with no problem.

  • S
    Sheena
    Reviewing
    Sleep
    I recommend this product
    Rated 5 out of 5 stars
    40 minutes ago
    5 Stars

    I am hooked! I love this innovative way of brushing my teeth. They feel like they have just had an official dental clean!

  • JH
    Jonathan H.
    Verified Buyer
    Reviewing
    Original Compostable Refill
    I recommend this product
    Rated 5 out of 5 stars
    1 hour ago
    We like it.

    We like the flavor and it seems to clean better than other toothpastes we've used. It's also nice to know we're not ingesting plastic from a plastic tube or creating unnecessary waste that's harmful to the environment.

  • L
    Laura
    Reviewing
    Immunity Compostable Refill
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    5 Stars

    Easy to use. I like not using the traditional tubes.

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