Immunity
Toothpaste

4.9

Toothpaste tablets featuring your daily dose of vitamins D3 + B12 
for better oral and systemic health.

Absorbed as you brush. No need to swallow.

Learn more

Immunity
Toothpaste

Toothpaste tablets featuring your daily dose of
vitamins D3 + B12 
for better oral and systemic health.

Absorbed as you brush. No need to swallow.

Learn more

4.9

245 Reviews

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Five Reasons to Switch to Duo

Co-founded by Dentists

Smiling person in a white blazer standing by a floral arrangement.

Stevie A. Roberts,

DMD

Founder of the dental practice Dentiste Kirkland in Seattle, WA, Dr. Roberts co-founded Duo toothpaste to bring better, science-backed ingredients to toothpaste tablets that work.

Smiling man wearing a white coat and tie with a gray background.

Robert E. Johnson,

DMD, MD

A graduate of the Department of Oral and Maxillofacial Surgery at the University of Washington. Dr. Johnson co-founded Duo with a commitment to oral and whole-body health.

How to Brush with Duo

Man holding a toothbrush and a small bottle, wearing a blue shirt.

1

Grab a Duo tablet

Man holds toothbrush and bottle, smiling with tablet in mouth.

2

Crush a tablet between your teeth

Man in blue holding a duo flossing product, smiling and demonstrating use.

3

Brush to activate foam

Smiling person in a blue shirt pointing towards the camera.

4

Spit and smile

4.9

254 Reviews

Duo Immunity

Duo Whitening Toothpaste pack and bottle for immunity with vitamins D and B12, 62 tablets.
Whitening Toothpaste Tablets

vitamin D3 (30mcg) + vitamin B12 (6mcg)

We topped off our original nHa whitening tablets with vitamin D3 and vitamin B12 to bolster the body’s defenses and lift mood. Absorbed into your bloodstream directly and efficiently as you brush. 

Subscribe and Save

SAVE 33%

4-month supply of 248 tablets

Glass printed bottle + compostable refill pouches

100% Guaranteed - return for full refund if not satisfied

Free shipping on all orders

One-time purchase

1 bottle of 62 tablets

Every 4 months - pause or cancel at anytime

whitens naturally 

without bleaching

nano-hydroxyapatite

for remineralizing teeth

antioxidants

for gum health

vitamin D3 (30mcg)

to bolster defenses

vitamin B12 (6mcg)

for mood support

vitamins absorbed

directly while brushing

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
'Black logo of the word 'duo' in lowercase letters.'

Standard
Toothpaste

Plastic-Free + Compostable Refills

Nano-Hydroxyapatite (Fluoride-Free) 

Vitamins & Supplements

SLS-Free & NO Harsh Chemicals

Hydrating Foam + Natural Flavors 

Reduces Sensitivity Without Numbing Agents

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Plastic free
for the planet

Duo is delivered in apothecary-grade, recyclable glass bottles. Subscription refills come in compostable pouches. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes
end up as trash
each year

Bottle labeled 'Duo Whitening Toothpaste' with tablets being poured from a packet.

Plastic free
for the planet

Duo is delivered in apothecary- grade, recyclable glass bottles. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes end up as trash each year

Reviews

4.8
Rated 4.8 out of 5 stars
Based on 317 reviews
317 reviews
  • LC
    Lori C.
    Verified Buyer
    Reviewing
    Immunity
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Surprisingly efficient

    These small tables leave your teeth super clean and I have noticed my teeth are whiter.

  • SP
    Suzann P.
    Verified Buyer
    Reviewing
    Original + 3 Bundle
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    Dou original

    Duo works very well. I would buy it again.

  • JC
    Judy C.
    Verified Buyer
    Reviewing
    Original + 3 Bundle
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Love this product!

    I love everything about this product starting with the little glass bottles. I've been trying to get rid of one- time use packaging for all my basic products like shampoos, laundry detergents etc. and the glass bottles along with the compostable refill pouches fit this goal perfectly. I've tried other tooth tablets before but I like the taste of these the best. They're minty but not overpowering. I've also been trying to pay attention to the ingredients in products and wanted to know more about the nano-hydroxyapatite in the product. I emailed the company and got a very detailed response from Mike, one of the co-founders of Duo. I will be a customer for life and am ordering starter sets for my grown children to get them started!

  • KJ
    Kara J.
    Verified Buyer
    Reviewing
    360 Bundle
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Enjoying this but with bad breath mornings

    I think that maybe if you floss, then use mouthwash, then use Duo, then you won’t have bad breath in the morning. But if you forget the mouthwash, then Duo doesn’t seem to have a strong enough mint flavor to account for better breath in the morning. I didn’t have this issue with regular tooth paste. It’s just an adjustment though, because I love the toothpaste itself and do actually think that it has made my teeth whiter already after just one month of use. I love the way it makes my teeth feel. It’s like squeaky clean feeling. I’d recommend it!