Immunity
Toothpaste

4.9

Toothpaste tablets featuring your daily dose of vitamins D3 + B12 
for better oral and systemic health.

Absorbed as you brush. No need to swallow.

Learn more

Immunity
Toothpaste

Toothpaste tablets featuring your daily dose of
vitamins D3 + B12 
for better oral and systemic health.

Absorbed as you brush. No need to swallow.

Learn more

4.9

321 Reviews

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Five Reasons to Switch to Duo

Co-founded by Dentists

Smiling person in a white blazer standing by a floral arrangement.

Stevie A. Roberts,

DMD

Founder of the dental practice Dentiste Kirkland in Seattle, WA, Dr. Roberts co-founded Duo toothpaste to bring better, science-backed ingredients to toothpaste tablets that work.

Smiling man wearing a white coat and tie with a gray background.

Robert E. Johnson,

DMD, MD

A graduate of the Department of Oral and Maxillofacial Surgery at the University of Washington. Dr. Johnson co-founded Duo with a commitment to oral and whole-body health.

How to Brush with Duo

Man holding a toothbrush and a small bottle, wearing a blue shirt.

1

Grab a Duo tablet

Man holds toothbrush and bottle, smiling with tablet in mouth.

2

Crush a tablet between your teeth

Man in blue holding a duo flossing product, smiling and demonstrating use.

3

Brush to activate foam

Smiling person in a blue shirt pointing towards the camera.

4

Spit and smile

Subscribe or Purchase One-Time

whitens naturally 

without bleaching

nano-hydroxyapatite

for remineralizing teeth

antioxidants

for gum health

vitamin D3 (30mcg)

to bolster defenses

vitamin B12 (6mcg)

for mood support

vitamins absorbed

directly while brushing

Brown bottle of Duo Whitening Toothpaste tablets with immunity support, containing vitamin D and B12.Duo Whitening Toothpaste pack and bottle for immunity with vitamins D and B12, 62 tablets.

vitamin D3 + vitamin B12

Immunity Whitening Toothpaste

4.9

321 Reviews

We topped off our original nHa whitening tablets with a perfectly portioned dose of vitamin D3 (30mcg) and vitamin B12 (6mcg) to bolster the body’s defenses and lift mood. Absorbed into your bloodstream directly and efficiently as you brush. 

1 Month (62 tablets) - SAVE 10%

1 Month (62 tablets) - SAVE 10%

1 Month (62 tablets) - SAVE 10%

One-Time Purchase

Save 40%

$28.00/month

$16.80/month

Save 40%

$18.00

$12.00/month

Save 33%

$18.00

$12.00/month

Save 33%

*** Subscriptions include one glass printed bottle that holds 62 tablets along with refills that come in compostable pouches. 

+ 100% Guaranteed - return for full refund if not satisfied
+ Free shipping on all orders over $40

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
'Black logo of the word 'duo' in lowercase letters.'

Standard
Toothpaste

Plastic-Free + Compostable Refills

Nano-Hydroxyapatite (Fluoride-Free) 

Vitamins & Supplements

SLS-Free & NO Harsh Chemicals

Hydrating Foam + Natural Flavors 

Reduces Sensitivity Without Numbing Agents

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Plastic free
for the planet

Duo is delivered in apothecary-grade, recyclable glass bottles. Subscription refills come in compostable pouches. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes
end up as trash
each year

Bottle labeled 'Duo Whitening Toothpaste' with tablets being poured from a packet.

Plastic free
for the planet

Duo is delivered in apothecary- grade, recyclable glass bottles. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes end up as trash each year

Reviews

4.8
Rated 4.8 out of 5 stars
Based on 328 reviews
328 reviews
  • JJ
    Jonathan J.
    Verified Buyer
    Reviewing
    Sleep Compostable Refill
    I recommend this product
    Rated 5 out of 5 stars
    5 hours ago
    Love It

    Love this toothpaste. No plastic tube to worry about and it helps me sleep like a baby. I’ll never go back to regular toothpaste again

  • MN
    Mari N.
    Verified Buyer
    Reviewing
    Sleep Compostable Refill
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    Perfect substitute for toothpaste

    Duo works better than toothpaste. Tastes fresh, makes plenty of foam for brushing your teeth, and leaves your teeth and whole mouth feeling clean and minty.

  • MN
    Mari N.
    Verified Buyer
    Reviewing
    Immunity Compostable Refill
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    Great proudct

    I wanted to stop using tubes of toothpaste and I am very happy to have found Duo. It's nice and minty, makes plenty of foam for brushing, and leaves my mouth feeling extra clean.

  • MK
    Mary Katherine F.
    Verified Buyer
    Reviewing
    Immunity Compostable Refill
    I recommend this product
    Rated 5 out of 5 stars
    4 days ago
    Love it!

    This is such a great way to travel, which is the reason I bought them in the first place. But now I use them at home as well. I love the additional benefits that come along for the ride!