Immunity
Toothpaste

4.9

Toothpaste tablets featuring your daily dose of vitamins D3 + B12 
for better oral and systemic health.

Absorbed as you brush. No need to swallow.

Learn more

Immunity
Toothpaste

Toothpaste tablets featuring your daily dose of
vitamins D3 + B12 
for better oral and systemic health.

Absorbed as you brush. No need to swallow.

Learn more

4.9

167 Reviews

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Five Reasons to Switch to Duo

Co-founded by Dentists

Smiling person in a white blazer standing by a floral arrangement.

Stevie A. Roberts,

DMD

Founder of the dental practice Dentiste Kirkland in Seattle, WA, Dr. Roberts co-founded Duo toothpaste to bring better, science-backed ingredients to toothpaste tablets that work.

Smiling man wearing a white coat and tie with a gray background.

Robert E. Johnson,

DMD, MD

A graduate of the Department of Oral and Maxillofacial Surgery at the University of Washington. Dr. Johnson co-founded Duo with a commitment to oral and whole-body health.

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
'Black logo of the word 'duo' in lowercase letters.'

Standard
Toothpaste

Plastic-Free + Compostable Refills

Nano-Hydroxyapatite (Fluoride-Free) 

Vitamins & Supplements

SLS-Free & NO Harsh Chemicals

Hydrating Foam + Natural Flavors 

Reduces Sensitivity Without Numbing Agents

How to Brush with Duo

Man holding a toothbrush and a small bottle, wearing a blue shirt.

1

Grab a Duo tablet

Man holds toothbrush and bottle, smiling with tablet in mouth.

2

Crush a tablet between your teeth

Man in blue holding a duo flossing product, smiling and demonstrating use.

3

Brush to activate foam

Smiling person in a blue shirt pointing towards the camera.

4

Spit and smile

Subscribe or Purchase One-Time

whitens naturally 

without bleaching

nano-hydroxyapatite

for remineralizing teeth

antioxidants

for gum health

vitamin D3 (30mcg)

to bolster defenses

vitamin B12 (6mcg)

for mood support

vitamins absorbed

directly while brushing

Brown bottle of Duo Whitening Toothpaste tablets with immunity support, containing vitamin D and B12.Duo Whitening Toothpaste pack and bottle for immunity with vitamins D and B12, 62 tablets.

vitamin D3 + vitamin B12

Immunity Whitening Toothpaste

4.9

167 Reviews

We topped off our original nHa whitening tablets with a perfectly portioned dose of vitamin D3 (30mcg) and vitamin B12 (6mcg) to bolster the body’s defenses and lift mood. Absorbed into your bloodstream directly and efficiently as you brush. 

1 Month (62 tablets) - SAVE 10%

1 Month (62 tablets) - SAVE 10%

1 Month (62 tablets) - SAVE 10%

One-Time Purchase

Save 33%

$18.00/month

$12.00/month

Save 33%

$18.00

$12.00/month

Save 33%

$18.00

$12.00/month

Save 33%

*** Subscriptions include one glass printed bottle that holds 62 tablets along with refills that come in compostable pouches. 

+ 100% Guaranteed - return for full refund if not satisfied
+ Free shipping on all orders over $20

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Plastic free
for the planet

Duo is delivered in apothecary-grade, recyclable glass bottles. Subscription refills come in compostable pouches. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes
end up as trash
each year

Bottle labeled 'Duo Whitening Toothpaste' with tablets being poured from a packet.

Plastic free
for the planet

Duo is delivered in apothecary- grade, recyclable glass bottles. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes end up as trash each year

Reviews

4.9
Rated 4.9 out of 5 stars
Based on 232 reviews
232 reviews
  • AG
    Ashley G.
    Verified Buyer
    Sleep
    Reviewing
    Sleep
    I recommend this product
    Rated 5 out of 5 stars
    6 days ago
    Great toothpaste tablet!

    I love these! I have been using them for a few weeks now and they are great! They are easy to crunch and foam up nicely just like a regular toothpaste and they are super easy to travel with!

  • NS
    Nina S.
    Verified Buyer
    Immunity
    Reviewing
    Immunity
    I recommend this product
    Rated 5 out of 5 stars
    6 days ago
    So much to like!

    I really like the idea of these chewable tablets that come in a glass bottle with refills in a paper pouch, so I bought them not knowing whether I would actually like the product. I’ve only been using it for about a week, but I love it. I shared with my adult daughter who is living with me and she also liked them. We have sonicare toothbrushes, so you just wet the toothbrush to the small tablet and start brushing! The taste is fresh and clean without being sweet, and they seem to do a really good job. I can’t speak to whether the mineralization actually works and my teeth don’t look whiter yet, but these little tablets have a lot going for them. I’m not sure 62 will last me a month because I sometimes brush my teeth three times a day! Love that fresh clean feeling.

  • AG
    Ashley G.
    Verified Buyer
    Sleep
    Reviewing
    Sleep
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Love them!

    The flavor is great! The tablets are soft to bite and break down nicely. The toothpaste also foams like normal toothpaste! Love this product!

  • KC
    Kimberly C.
    Verified Buyer
    Energy
    Reviewing
    Energy
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Was skeptical…

    However, I LOVE duo! I tried the Energy and Original tablets and the velvety foam is super gentle on my sensitive teeth. Store bought big pharma anti-sensitivity brands are a thing of the past for me!

Reviews LoadedReviews Added