Immunity
Toothpaste

Toothpaste tablets featuring vitamins D3 + B12 

for better oral and systemic health.

Learn more

4.9

167 Reviews

Immunity
Toothpaste

4.9

Toothpaste tablets featuring vitamins D3 + B12 for better oral and systemic health.

Learn more

Why Duo?

Better-for-you
toothpaste tablets

Whitens Naturally.

Without peroxides or
chemicals that strip enamel.

Travel-Ready.

TSA-compliant and mess-free convenience.

Vegan and Cruelty-Free

Clean ingredients with all-natural flavors for a feel-good routine.

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'

Why Duo?

Better-for-you toothpaste tablets

Whitens Naturally.

Without peroxides or chemicals that strip enamel.

Decreases Sensitivity

Core ingredients, like nHA, insulate nerves without numbing agents.

Hydrating Foam.

Free from SLS and drying agents for healthy balance.

Vitamins & Supplements.

Absorbed as you brush for oral and systemic health.

Travel-Ready

TSA-compliant and mess-free convenience.

Vegan and Cruelty-Free

Clean ingredients with all-natural flavors for a feel-good routine.

Hand holding a wooden toothbrush with a white pill on green bristles.

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
A wooden toothbrush with green bristles and a white tablet on top.
A wooden toothbrush with green bristles and a white tablet on top.

How to brush with Duo

1

Chew tablet
to break
down

2

Wet your toothbrush

3

Brush to activate
foam

4

Spit and
smile

Watch explainer with Dr. Stevie Roberts

The Power of 

Mucosal Absorption

Keep your immune system strong in all seasons with highly bioavailable vitamin D3.

Elevate mood and neurological function with the ideal dose of vitamin B12.

A woman with a towel around her shoulders brushing her teeth, smiling.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

The Best Toothpaste Tablets

"These are fabulous! They aren't powdery when you chew them like some are, and my teeth feel super clean and minty after I'm done. I'm going to keep buying them from now on."

-Erik D.

4.9

167 Reviews

Easy Way to Get Vitamin D3

"I like knowing that my toothpaste delivers the vitamin D (200% the RDA)  I need twice a day, every day! It has a nice flavor, too... And you can recycle the glass bottle, unlike a plastic tube."

- Lucy H.

Subscribe or Purchase One-Time

whitens naturally 

without bleaching

nano-hydroxyapatite

for remineralizing teeth

antioxidants

for gum health

vitamin D3 (30mcg)

to bolster defenses

vitamin B12 (6mcg)

for mood support

vitamins absorbed

directly while brushing

Brown bottle of Duo Whitening Toothpaste tablets with immunity support, containing vitamin D and B12.Duo Whitening Toothpaste pack and bottle for immunity with vitamins D and B12, 62 tablets.

vitamin D3 + vitamin B12

Immunity Whitening Toothpaste

4.9

167 Reviews

We topped off our baseline nHa whitening tablets with a perfectly portioned dose of vitamin D3 (30mcg) and vitamin B12 (6mcg) to bolster the body’s defenses and lift mood. Absorbed into your bloodstream directly and efficiently as you brush. 

1 Month (62 tablets) - SAVE 10%

1 Month (62 tablets) - SAVE 10%

1 Month (62 tablets) - SAVE 10%

One-Time Purchase

Save 33%

$18.00/month

$12.00/month

Save 33%

$18.00

$12.00/month

Save 33%

$18.00

$12.00/month

Save 33%

*** Subscriptions include one glass printed bottle that holds 62 tablets along with refills that come in compostable pouches. 

+ 100% Guaranteed - return for full refund if not satisfied
+ Free shipping on all orders over $20

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Plastic free
for the planet

Duo is delivered in apothecary-grade, recyclable glass bottles. Subscription refills come in compostable pouches. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes
end up as trash
each year

Bottle labeled 'Duo Whitening Toothpaste' with tablets being poured from a packet.

Plastic free
for the planet

Duo is delivered in apothecary- grade, recyclable glass bottles. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes end up as trash each year

Reviews

4.8
Rated 4.8 out of 5 stars
Based on 345 reviews
345 reviews
  • MJ
    Mitzi Jo C.
    Verified Buyer
    Reviewing
    Original + 3 Bundle
    I recommend this product
    Rated 5 out of 5 stars
    6 minutes ago
    Best Toothpaste

    love it!

  • JD
    Jennifer D.
    Verified Buyer
    Reviewing
    Original Compostable Refill
    I recommend this product
    Rated 5 out of 5 stars
    3 hours ago
    Never going back to chemical toothpaste

    I love Duo toothpaste tablets. They foam up and clean as well as commercial toothpaste without ingesting questionable ingredients.

  • DC
    Donna C.
    Verified Buyer
    Reviewing
    Original
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    Works great

    I received a sample of the energy and wish I had ordered that are could send these back for those. The taste of the energy is way better also seems to suds up more as the original doesn’t suds up.

  • SS
    Sandy S.
    Verified Buyer
    Reviewing
    Original
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Awesome

    Luv it. Luv the immunity one too..I use the original in the am and the immunity on pm... I see and feel a difference .