Immunity
Toothpaste

Toothpaste tablets featuring vitamins D3 + B12 

for better oral and systemic health.

Learn more

4.9

167 Reviews

Immunity
Toothpaste

4.9

Toothpaste tablets featuring vitamins D3 + B12 for better oral and systemic health.

Learn more

Why Duo?

Better-for-you
toothpaste tablets

Whitens Naturally.

Without peroxides or
chemicals that strip enamel.

Hydrating Foam.

Free from SLS and drying
agents for fresher breath.

Vitamins & Supplements.

Absorbed as you brush for
oral and systemic health.

Decreases Sensitivity.

Core ingredients, like nHA, insulate nerves without numbing agents.

Travel-Ready.

TSA-compliant and mess-free convenience.

Vegan and Cruelty-Free

Clean ingredients with all-natural flavors for a feel-good routine.

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'

Why Duo?

Better-for-you toothpaste tablets

Whitens Naturally.

Without peroxides or chemicals that strip enamel.

Decreases Sensitivity

Core ingredients, like nHA, insulate nerves without numbing agents.

Hydrating Foam.

Free from SLS and drying agents for healthy balance.

Vitamins & Supplements.

Absorbed as you brush for oral and systemic health.

Travel-Ready

TSA-compliant and mess-free convenience.

Vegan and Cruelty-Free

Clean ingredients with all-natural flavors for a feel-good routine.

Hand holding a wooden toothbrush with a white pill on green bristles.

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
A wooden toothbrush with green bristles and a white tablet on top.
A wooden toothbrush with green bristles and a white tablet on top.

How to brush with Duo

1

Chew tablet
to break
down

2

Wet your toothbrush

3

Brush to activate
foam

4

Spit and
smile

Watch explainer with Dr. Stevie Roberts

The Power of 

Mucosal Absorption

Your mouth has thousands of capillaries that absorb nutrients directly into the bloodstream while you brush - no swallowing needed.

Keep your immune system strong in all seasons with highly bioavailable vitamin D3.

Elevate mood and neurological function with the ideal dose of vitamin B12.

A woman with a towel around her shoulders brushing her teeth, smiling.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

The Best Toothpaste Tablets

"These are fabulous! They aren't powdery when you chew them like some are, and my teeth feel super clean and minty after I'm done. I'm going to keep buying them from now on."

-Erik D.

4.9

167 Reviews

Easy Way to Get Vitamin D3

"I like knowing that my toothpaste delivers the vitamin D (200% the RDA)  I need twice a day, every day! It has a nice flavor, too... And you can recycle the glass bottle, unlike a plastic tube."

- Lucy H.

Subscribe or Purchase One-Time

whitens naturally 

without bleaching

nano-hydroxyapatite

for remineralizing teeth

antioxidants

for gum health

vitamin D3 (30mcg)

to bolster defenses

vitamin B12 (6mcg)

for mood support

vitamins absorbed

directly while brushing

Brown bottle of Duo Whitening Toothpaste tablets with immunity support, containing vitamin D and B12.Duo Whitening Toothpaste pack and bottle for immunity with vitamins D and B12, 62 tablets.

vitamin D3 + vitamin B12

Immunity Whitening Toothpaste

4.9

167 Reviews

We topped off our baseline nHa whitening tablets with a perfectly portioned dose of vitamin D3 (30mcg) and vitamin B12 (6mcg) to bolster the body’s defenses and lift mood. Absorbed into your bloodstream directly and efficiently as you brush. 

1 Month (62 tablets) - SAVE 10%

1 Month (62 tablets) - SAVE 10%

1 Month (62 tablets) - SAVE 10%

One-Time Purchase

Save 33%

$18.00/month

$12.00/month

Save 33%

$18.00

$12.00/month

Save 33%

$18.00

$12.00/month

Save 33%

*** Subscriptions include one glass printed bottle that holds 62 tablets along with refills that come in compostable pouches. 

+ 100% Guaranteed - return for full refund if not satisfied
+ Free shipping on all orders over $20

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Plastic free
for the planet

Duo is delivered in apothecary-grade, recyclable glass bottles. Subscription refills come in compostable pouches. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes
end up as trash
each year

Bottle labeled 'Duo Whitening Toothpaste' with tablets being poured from a packet.

Plastic free
for the planet

Duo is delivered in apothecary- grade, recyclable glass bottles. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes end up as trash each year

Reviews

4.8
Rated 4.8 out of 5 stars
Based on 317 reviews
317 reviews
  • LC
    Lori C.
    Verified Buyer
    Reviewing
    Immunity
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Surprisingly efficient

    These small tables leave your teeth super clean and I have noticed my teeth are whiter.

  • SP
    Suzann P.
    Verified Buyer
    Reviewing
    Original + 3 Bundle
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    Dou original

    Duo works very well. I would buy it again.

  • JC
    Judy C.
    Verified Buyer
    Reviewing
    Original + 3 Bundle
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Love this product!

    I love everything about this product starting with the little glass bottles. I've been trying to get rid of one- time use packaging for all my basic products like shampoos, laundry detergents etc. and the glass bottles along with the compostable refill pouches fit this goal perfectly. I've tried other tooth tablets before but I like the taste of these the best. They're minty but not overpowering. I've also been trying to pay attention to the ingredients in products and wanted to know more about the nano-hydroxyapatite in the product. I emailed the company and got a very detailed response from Mike, one of the co-founders of Duo. I will be a customer for life and am ordering starter sets for my grown children to get them started!

  • KJ
    Kara J.
    Verified Buyer
    Reviewing
    360 Bundle
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Enjoying this but with bad breath mornings

    I think that maybe if you floss, then use mouthwash, then use Duo, then you won’t have bad breath in the morning. But if you forget the mouthwash, then Duo doesn’t seem to have a strong enough mint flavor to account for better breath in the morning. I didn’t have this issue with regular tooth paste. It’s just an adjustment though, because I love the toothpaste itself and do actually think that it has made my teeth whiter already after just one month of use. I love the way it makes my teeth feel. It’s like squeaky clean feeling. I’d recommend it!