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Immunity
Toothpaste
Toothpaste tablets featuring vitamins D3 + B12
for better oral and systemic health.
Learn more
4.9
167 Reviews
Immunity
Toothpaste
4.9
Toothpaste tablets featuring vitamins D3 + B12 for better oral and systemic health.
Learn more
Why Duo?
Better-for-you
toothpaste tablets
Whitens Naturally.
Without peroxides or
chemicals that strip enamel.
Hydrating Foam.
Free from SLS and drying
agents for fresher breath.
Vitamins & Supplements.
Absorbed as you brush for
oral and systemic health.
Decreases Sensitivity.
Core ingredients, like nHA, insulate nerves without numbing agents.
Travel-Ready.
TSA-compliant and mess-free convenience.
Vegan and Cruelty-Free
Clean ingredients with all-natural flavors for a feel-good routine.
Trusted by the industry
Why Duo?
Better-for-you toothpaste tablets
Whitens Naturally.
Without peroxides or chemicals that strip enamel.
Decreases Sensitivity
Core ingredients, like nHA, insulate nerves without numbing agents.
Hydrating Foam.
Free from SLS and drying agents for healthy balance.
Vitamins & Supplements.
Absorbed as you brush for oral and systemic health.
Travel-Ready
TSA-compliant and mess-free convenience.
Vegan and Cruelty-Free
Clean ingredients with all-natural flavors for a feel-good routine.
Trusted by the industry
Trusted by the industry
How to brush with Duo
1
Chew tablet
to break
down
2
Wet your toothbrush
3
Brush to activate
foam
4
Spit and
smile
Watch explainer with Dr. Stevie Roberts
The Power of
Mucosal Absorption
Your mouth has thousands of capillaries that absorb nutrients directly into the bloodstream while you brush - no swallowing needed.
Keep your immune system strong in all seasons with highly bioavailable vitamin D3.
Elevate mood and neurological function with the ideal dose of vitamin B12.
VEGAN
NON-TOXIC
SLS-FREE
DENTIST-CREATED
CRUELTY-FREE
FLUORIDE-FREE
PLASTIC-FREE
MADE IN U.S.
The Best Toothpaste Tablets
"These are fabulous! They aren't powdery when you chew them like some are, and my teeth feel super clean and minty after I'm done. I'm going to keep buying them from now on."
-Erik D.
4.9
167 Reviews
Easy Way to Get Vitamin D3
"I like knowing that my toothpaste delivers the vitamin D (200% the RDA) I need twice a day, every day! It has a nice flavor, too... And you can recycle the glass bottle, unlike a plastic tube."
- Lucy H.
Subscribe or Purchase One-Time
whitens naturally
without bleaching
nano-hydroxyapatite
for remineralizing teeth
antioxidants
for gum health
vitamin D3 (30mcg)
to bolster defenses
vitamin B12 (6mcg)
for mood support
vitamins absorbed
directly while brushing
vitamin D3 + vitamin B12
4.9
167 Reviews
We topped off our baseline nHa whitening tablets with a perfectly portioned dose of vitamin D3 (30mcg) and vitamin B12 (6mcg) to bolster the body’s defenses and lift mood. Absorbed into your bloodstream directly and efficiently as you brush.
1 Month (62 tablets) - SAVE 10%
1 Month (62 tablets) - SAVE 10%
1 Month (62 tablets) - SAVE 10%
One-Time Purchase
Save 33%
$18.00/month
$12.00/month
Save 33%
$18.00
$12.00/month
Save 33%
$18.00
$12.00/month
Save 33%
*** Subscriptions include one glass printed bottle that holds 62 tablets along with refills that come in compostable pouches.
+ 100% Guaranteed - return for full refund if not satisfied
+ Free shipping on all orders over $20
VITAMINS D3 + B12 ABSORBED AS YOU BRUSH
Your mouth has thousands of capillaries that absorb nutrients directly into the bloodstream while you brush - no swallowing needed.
Keep your immune system strong in all seasons with highly bioavailable vitamin D3.
Elevate mood and neurological function with the ideal dose of vitamin B12.
HOW TO BRUSH WITH DUO
Wet your toothbrush and pop a tablet in your mouth. Crunch to break it up into tiny pieces. Start brushing to activate foam. Our natural, hydrating foam will build and reach its peak in about 30 seconds.
1
Chew tablet to break down
2
Wet your toothbrush
3
Brush to activate foam
4
Spit and smile
CLEAN INGREDIENTS
30mcg vitamin D3
bolsters immune defenses and mood
6mcg vitamin B12 (methylcobalamin)
boosts mood
nano-hydroxyapatite
remineralizes, whitens & reduces sensitivity
xylitol (birch extract)
promotes saliva production
calcium carbonate
natural polisher
sodium bicarbonate
natural polisher
cellulose
provides structure to tablets
xanthan gum
protects against dry mouth
magnesium stearate
vegetable-derived powder lubricant
hydrated silica
natural polisher
menthol
cooling, soothing sensation
sage, peppermint, wintergreen, spearmint
natural flavor
vitamin C, vitamin E
gum health
VEGAN
NON-TOXIC
SLS-FREE
DENTIST-CREATED
CRUELTY-FREE
FLUORIDE-FREE
PLASTIC-FREE
MADE IN U.S.
VEGAN
NON-TOXIC
SLS-FREE
DENTIST-CREATED
CRUELTY-FREE
FLUORIDE-FREE
PLASTIC-FREE
MADE IN U.S.
Plastic free
for the planet
Duo is delivered in apothecary-grade, recyclable glass bottles. Subscription refills come in compostable pouches. It’s the future of toothpaste and better for all of us.
500
years
to break down a
single plastic
toothpaste tube
1.5
billion
plastic tubes
end up as trash
each year
Plastic free
for the planet
Duo is delivered in apothecary- grade, recyclable glass bottles. It’s the future of toothpaste and better for all of us.
500
years
to break down a
single plastic
toothpaste tube
1.5
billion
plastic tubes end up as trash each year
Reviews
- MCMelissa C.Verified BuyerReviewingImmunityI recommend this productRated 5 out of 5 stars3 minutes agoSo impressed!
I have been using another brand of toothpaste bits for several years. On a whim, I decided to give these a try. They are more expensive than my previous brand, but I have been converted! I love how clean my teeth feel after brushing. The foam is quite thick, but I like that it's not runny. The flavor is good. My mouth is less dry at night. Morning breath is not bad anymore. I like the texture of these better as well. They are softer and feel better on my teeth and gums. I tried a sample of the melatonin and will buy that next. I believe, after trying it three times, that it really works.
- GBGina B.Verified BuyerReviewingImmunityI recommend this productRated 5 out of 5 stars13 hours agoDual purpose and very clean!
This isn't toothpaste...it is different, so it takes a minute to get used to it. I find the taste pleasant, but most importantly, I immediately noticed how much cleaner my teeth feel. Seriously, I can tell! My teeth sometimes squeak when brushing. I'm in love with the product, the convenience for traveling (taking these on a plane for a quick refresh!). And, I love the idea of less in the landfill which has become my goal for all products I purchase in 2025.
- GBGina B.Verified BuyerReviewingSleepI recommend this productRated 5 out of 5 stars13 hours agoClean, Clean, Clean
This isn't toothpaste...it is different, so it takes a minute to get used to it. I find the taste pleasant, but most importantly, I immediately noticed how much cleaner my teeth feel. Seriously, I can tell! My teeth sometimes squeak when brushing. I'm in love with the product, the convenience for traveling (taking these on a plane for a quick refresh!). And, I love the idea of less in the landfill which has become my goal for all products I purchase in 2025.
- KPKim P.Verified BuyerReviewingImmunityI recommend this productRated 5 out of 5 starsYesterdayTruly Amazed at the Results
So I have gum disease and have had gum surgery, leaving my teeth extremely sensitive to hot/cold. I have used so many toothpastes for sensitive teeth with zero improvement. I was shocked at the results after using duo for about a week. I have almost ZERO sensitivity now. Honestly, I can hardly believe the difference. It was so dramatic I was shocked. I can't wait to go in for my next quarterly cleaning! The other thing I love is the super fresh mint flavor. I am a user for life, and I'm so grateful I found this product!
