Immunity
Toothpaste

Toothpaste tablets featuring vitamins D3 + B12 

for better oral and systemic health.

Learn more

4.9

167 Reviews

Immunity
Toothpaste

4.9

Toothpaste tablets featuring vitamins D3 + B12 for better oral and systemic health.

Learn more

Why Duo?

Better-for-you
toothpaste tablets

Whitens Naturally.

Without peroxides or
chemicals that strip enamel.

Travel-Ready.

TSA-compliant and mess-free convenience.

Vegan and Cruelty-Free

Clean ingredients with all-natural flavors for a feel-good routine.

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'

Why Duo?

Better-for-you toothpaste tablets

Whitens Naturally.

Without peroxides or chemicals that strip enamel.

Decreases Sensitivity

Core ingredients, like nHA, insulate nerves without numbing agents.

Hydrating Foam.

Free from SLS and drying agents for healthy balance.

Vitamins & Supplements.

Absorbed as you brush for oral and systemic health.

Travel-Ready

TSA-compliant and mess-free convenience.

Vegan and Cruelty-Free

Clean ingredients with all-natural flavors for a feel-good routine.

Hand holding a wooden toothbrush with a white pill on green bristles.

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
A wooden toothbrush with green bristles and a white tablet on top.
A wooden toothbrush with green bristles and a white tablet on top.

How to brush with Duo

1

Chew tablet
to break
down

2

Wet your toothbrush

3

Brush to activate
foam

4

Spit and
smile

Watch explainer with Dr. Stevie Roberts

The Power of 

Mucosal Absorption

Keep your immune system strong in all seasons with highly bioavailable vitamin D3.

Elevate mood and neurological function with the ideal dose of vitamin B12.

A woman with a towel around her shoulders brushing her teeth, smiling.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

The Best Toothpaste Tablets

"These are fabulous! They aren't powdery when you chew them like some are, and my teeth feel super clean and minty after I'm done. I'm going to keep buying them from now on."

-Erik D.

4.9

167 Reviews

Easy Way to Get Vitamin D3

"I like knowing that my toothpaste delivers the vitamin D (200% the RDA)  I need twice a day, every day! It has a nice flavor, too... And you can recycle the glass bottle, unlike a plastic tube."

- Lucy H.

Subscribe or Purchase One-Time

whitens naturally 

without bleaching

nano-hydroxyapatite

for remineralizing teeth

antioxidants

for gum health

vitamin D3 (30mcg)

to bolster defenses

vitamin B12 (6mcg)

for mood support

vitamins absorbed

directly while brushing

Brown bottle of Duo Whitening Toothpaste tablets with immunity support, containing vitamin D and B12.Duo Whitening Toothpaste pack and bottle for immunity with vitamins D and B12, 62 tablets.

vitamin D3 + vitamin B12

Immunity Whitening Toothpaste

4.9

167 Reviews

We topped off our baseline nHa whitening tablets with a perfectly portioned dose of vitamin D3 (30mcg) and vitamin B12 (6mcg) to bolster the body’s defenses and lift mood. Absorbed into your bloodstream directly and efficiently as you brush. 

1 Month (62 tablets) - SAVE 10%

1 Month (62 tablets) - SAVE 10%

1 Month (62 tablets) - SAVE 10%

One-Time Purchase

Save 33%

$18.00/month

$12.00/month

Save 33%

$18.00

$12.00/month

Save 33%

$18.00

$12.00/month

Save 33%

*** Subscriptions include one glass printed bottle that holds 62 tablets along with refills that come in compostable pouches. 

+ 100% Guaranteed - return for full refund if not satisfied
+ Free shipping on all orders over $20

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Plastic free
for the planet

Duo is delivered in apothecary-grade, recyclable glass bottles. Subscription refills come in compostable pouches. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes
end up as trash
each year

Bottle labeled 'Duo Whitening Toothpaste' with tablets being poured from a packet.

Plastic free
for the planet

Duo is delivered in apothecary- grade, recyclable glass bottles. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes end up as trash each year

Reviews

4.8
Rated 4.8 out of 5 stars
Based on 447 reviews
447 reviews
  • CP
    Christy P.
    Verified Buyer
    Reviewing
    Original
    I recommend this product
    Rated 5 out of 5 stars
    3 minutes ago
    Great choice for switching from plastic and harmful ingredients

    I switched to Duo because I wanted a clean, non plastic encased toothpaste. I am very pleased with it and knew I made a great choice when my dentist commented on how clean my teeth are!

  • SB
    Sarah B.
    Verified Buyer
    Reviewing
    Immunity
    I recommend this product
    Rated 5 out of 5 stars
    2 hours ago
    Awesome tablets

    So far I have tried the Immunity, sleep and energy Duo tablets. I love how they foam up with brushing. I was skeptical to try these because of the flavor but have been pleasantly surprised by all. I really like the mint and sage. I have been using one of the other toothpaste tablets for over a year now and I liked those but am much happier with these. They are a little spendy but I do appreciate knowing what I am putting in my body.

  • TM
    Tiffany M.
    Verified Buyer
    Reviewing
    Original Compostable Refill
    I recommend this product
    Rated 5 out of 5 stars
    2 weeks ago
    Re-order

    Love these compostable refills.

  • K
    Katelyn
    Reviewing
    Original
    I recommend this product
    Rated 5 out of 5 stars
    2 weeks ago
    5 Stars

    Ive only been using it for 2 months but am very happy so far with both the product and the customer service. The subscriptions deliver perfectly on time.