Energy
Toothpaste

Toothpaste tablets to boost energy and
elevate your mood. Infused with caffeine
and vitamin B12.

Learn more

4.9

185 Reviews

Energy
Toothpaste

4.9

Toothpaste tablets to boost energy and

elevate your mood.

Infused with caffeine and vitamin B12.

Learn more

Woman smiling while holding a supplement bottle against a yellow background.

Caffeine + B12:

How It's Absorbed

Your mouth is full of absorbent tissue that delivers the caffeine and vitamin B12 directly into your bloodstream while you brush - no swallowing needed.

Purple circle with a white crescent moon and star icon.

Caffeine is felt almost immediately, no more waiting for coffee to be metabolized. 10mg of caffeine = 1/5 cup of coffee.

Simple moon and star icon on a purple background.

Elevate mood and neurological function with the ideal dose of 6mcg of vitamin B12.

Why Duo?

Better-for-you
toothpaste tablets

Whitens Naturally.

Without peroxides or
chemicals that strip enamel.

Vitamins & Supplements.

Absorbed as you brush for
oral and systemic health.

Travel-Ready.

TSA-compliant and mess-free convenience.

Vegan and Cruelty-Free

Clean ingredients with all-natural flavors for a feel-good routine.

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'

Why Duo?

Better-for-you toothpaste tablets

Whitens Naturally.

Without peroxides or chemicals that strip enamel.

Decreases Sensitivity

Core ingredients, like nHA, insulate nerves without numbing agents.

Hydrating Foam.

Free from SLS and drying agents for healthy balance.

Vitamins & Supplements.

Absorbed as you brush for oral and systemic health.

Travel-Ready

TSA-compliant and mess-free convenience.

Vegan and Cruelty-Free

Clean ingredients with all-natural flavors for a feel-good routine.

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
Smiling person in yellow shirt holding a small bottle, pouring out contents into their hand.

Caffeine + B12:

How It's Absorbed

Your mouth is full of absorbent tissue that delivers the caffeine and vitamin B12 directly into your bloodstream while you brush - no swallowing needed.

Simple moon and star icon on a purple background.

Elevate mood and neurological function with the ideal dose of 6mcg of vitamin B12.

Smiling person in yellow shirt holding a small bottle, pouring out contents into their hand.

Caffeine + B12:

How It's Absorbed

Your mouth is full of absorbent tissue that delivers the caffeine and vitamin B12 directly into your bloodstream while you brush - no swallowing needed.

Purple circle with a white crescent moon and star icon.

Caffeine is felt almost immediately, no more waiting for coffee to be metabolized. (10mg of caffeine = 1/5 cup of coffee)

Simple moon and star icon on a purple background.

Elevate mood and neurological function with the ideal dose of 6mcg of vitamin B12.

How to brush with Duo

1

Chew tablet
to break
down

2

Wet your toothbrush

3

Brush to activate
foam

4

Spit and
smile

Watch explainer with Dr. Stevie Roberts

Hand holding wooden toothbrush with a white pill on bristles, against yellow background.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Best Toothpaste Tablets

"These are fabulous! They aren't powdery when you chew them like some are, and my teeth feel super clean and minty after I'm done. I'm going to keep buying them from now on."

-Erik D.

4.9

194 Reviews

LOVE LOVE LOVE

"I started brushing with Energy to give my mornings a boost before I got to my morning cup of coffee. I now use them for a mid-day refresh and it's become such a lovely (and healthy) ritual. The flavor is refreshing, more foam than any other tablets I've tried, and I can't get over the added benefits of the caffeine & B12."

- Hannah G.

Purchase One-Time or Subscribe

whitens naturally 

without bleaching

nano-hydroxyapatite

for remineralizing teeth

antioxidants

for gum health

caffeine (10mg)

boosts performance

vitamin B12 (6mcg)

elevates mood & energy

vitamins absorbed

directly while brushing

Amber bottle of Duo Whitening Toothpaste tablets with caffeine and vitamin B12.Two jars and two packets of Duo whitening toothpaste tablets in Sleep and Original varieties.

10mg of caffeine || 6mcg of vitamin B12

Energy Whitening

Toothpaste Tablets

4.9

194 Reviews

Get a boost while you brush with Duo tablets for energy, mood and metabolism support. We topped off our signature oral microbiome-balancing tablets with a perfectly portioned dose of caffeine (10mg), vitamin B12 (6mcg), and L-theanine (2.5mg) to invigorate your system. A feel-good start to the day or whenever you need a pick-me-up. Cinnamon mint chai flavor.

1 Bottle (62 tablets) 

1 Bottle (62 tablets) 

1 Bottle (62 tablets) 

One-Time Purchase

Monthly Delivery

***

Subscribe to

save up to 33%

$18.00

$12.00/month

Save 33%

$18.00

$12.00/month

Save 33%

$18.00

$12.00/month

Save 33%

*** Subscriptions include glass printed bottles of Sleep and Original (1 of each) that hold 62 tablets each along with refills that come in compostable pouches. 

+ 100% Guaranteed - return for full refund if not satisfied
+ Free shipping on all orders over $20

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Plastic free
for the planet

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes
end up as trash
each year

Duo Whitening Toothpaste tablets with caffeine and vitamin B12, displayed with packaging.

Plastic free
for the planet

Duo is delivered in apothecary- grade, recyclable glass bottles. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes end up as trash each year

Reviews

4.8
Rated 4.8 out of 5 stars
Based on 450 reviews
450 reviews
  • SJ
    sharon j.
    Verified Buyer
    Reviewing
    Original Compostable Refill
    I recommend this product
    Rated 5 out of 5 stars
    4 minutes ago
    Duo toothpaste

    I love the refillable bottles and the quality of the little pills. So convenient and economical

  • AS
    Anna S.
    Verified Buyer
    Reviewing
    Original Compostable Refill
    I recommend this product
    Rated 5 out of 5 stars
    1 month ago
    Nearly Perfect Toothpaste!

    I switched over to duo when my previous tablet toothpaste changed their refill program. I was initially drawn to duo because of their low-waste, compostable packaging program. I love that when I receive my shipment, there isn’t any extra material, just what I ordered! The ingredients of duo toothpaste are another plus, and it has to be one of the shortest ingredients lists for chewable toothpastes! My only note is that it can sometimes be hard to get it to foam up and I have to wet my toothbrush two or three times first.

  • CP
    Christy P.
    Verified Buyer
    Reviewing
    Original
    I recommend this product
    Rated 5 out of 5 stars
    3 months ago
    Great choice for switching from plastic and harmful ingredients

    I switched to Duo because I wanted a clean, non plastic encased toothpaste. I am very pleased with it and knew I made a great choice when my dentist commented on how clean my teeth are!

  • SB
    Sarah B.
    Verified Buyer
    Reviewing
    Immunity
    I recommend this product
    Rated 5 out of 5 stars
    3 months ago
    Awesome tablets

    So far I have tried the Immunity, sleep and energy Duo tablets. I love how they foam up with brushing. I was skeptical to try these because of the flavor but have been pleasantly surprised by all. I really like the mint and sage. I have been using one of the other toothpaste tablets for over a year now and I liked those but am much happier with these. They are a little spendy but I do appreciate knowing what I am putting in my body.