Energy
Toothpaste

Toothpaste tablets to boost energy and
elevate your mood. Infused with caffeine
and vitamin B12.

Learn more

4.9

185 Reviews

Energy
Toothpaste

4.9

Toothpaste tablets to boost energy and

elevate your mood.

Infused with caffeine and vitamin B12.

Learn more

Woman smiling while holding a supplement bottle against a yellow background.

Caffeine + B12:

How It's Absorbed

Your mouth is full of absorbent tissue that delivers the caffeine and vitamin B12 directly into your bloodstream while you brush - no swallowing needed.

Purple circle with a white crescent moon and star icon.

Caffeine is felt almost immediately, no more waiting for coffee to be metabolized. 10mg of caffeine = 1/5 cup of coffee.

Simple moon and star icon on a purple background.

Elevate mood and neurological function with the ideal dose of 6mcg of vitamin B12.

Why Duo?

Better-for-you
toothpaste tablets

Whitens Naturally.

Without peroxides or
chemicals that strip enamel.

Hydrating Foam.

Free from SLS and drying
agents for fresher breath.

Vitamins & Supplements.

Absorbed as you brush for
oral and systemic health.

Decreases Sensitivity.

Core ingredients, like nHA, insulate nerves without numbing agents.

Travel-Ready.

TSA-compliant and mess-free convenience.

Vegan and Cruelty-Free

Clean ingredients with all-natural flavors for a feel-good routine.

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'

Why Duo?

Better-for-you toothpaste tablets

Whitens Naturally.

Without peroxides or chemicals that strip enamel.

Decreases Sensitivity

Core ingredients, like nHA, insulate nerves without numbing agents.

Hydrating Foam.

Free from SLS and drying agents for healthy balance.

Vitamins & Supplements.

Absorbed as you brush for oral and systemic health.

Travel-Ready

TSA-compliant and mess-free convenience.

Vegan and Cruelty-Free

Clean ingredients with all-natural flavors for a feel-good routine.

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
Smiling person in yellow shirt holding a small bottle, pouring out contents into their hand.

Caffeine + B12:

How It's Absorbed

Your mouth is full of absorbent tissue that delivers the caffeine and vitamin B12 directly into your bloodstream while you brush - no swallowing needed.

Purple circle with a white crescent moon and star icon.

Caffeine is felt almost immediately- no more waiting for coffee to be metabolized. 10mg of caffeine = 1/5 cup of coffee.

Simple moon and star icon on a purple background.

Elevate mood and neurological function with the ideal dose of 6mcg of vitamin B12.

Smiling person in yellow shirt holding a small bottle, pouring out contents into their hand.

Caffeine + B12:

How It's Absorbed

Your mouth is full of absorbent tissue that delivers the caffeine and vitamin B12 directly into your bloodstream while you brush - no swallowing needed.

Purple circle with a white crescent moon and star icon.

Caffeine is felt almost immediately, no more waiting for coffee to be metabolized. (10mg of caffeine = 1/5 cup of coffee)

Simple moon and star icon on a purple background.

Elevate mood and neurological function with the ideal dose of 6mcg of vitamin B12.

How to brush with Duo

1

Chew tablet
to break
down

2

Wet your toothbrush

3

Brush to activate
foam

4

Spit and
smile

Watch explainer with Dr. Stevie Roberts

Hand holding wooden toothbrush with a white pill on bristles, against yellow background.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Best Toothpaste Tablets

"These are fabulous! They aren't powdery when you chew them like some are, and my teeth feel super clean and minty after I'm done. I'm going to keep buying them from now on."

-Erik D.

4.9

194 Reviews

LOVE LOVE LOVE

"I started brushing with Energy to give my mornings a boost before I got to my morning cup of coffee. I now use them for a mid-day refresh and it's become such a lovely (and healthy) ritual. The flavor is refreshing, more foam than any other tablets I've tried, and I can't get over the added benefits of the caffeine & B12."

- Hannah G.

Purchase One-Time or Subscribe

whitens naturally 

without bleaching

nano-hydroxyapatite

for remineralizing teeth

antioxidants

for gum health

caffeine (10mg)

boosts performance

vitamin B12 (6mcg)

elevates mood & energy

vitamins absorbed

directly while brushing

Amber bottle of Duo Whitening Toothpaste tablets with caffeine and vitamin B12.Two jars and two packets of Duo whitening toothpaste tablets in Sleep and Original varieties.

10mg of caffeine || 6mcg of vitamin B12

Energy Whitening

Toothpaste Tablets

4.9

194 Reviews

Get a boost while you brush with Duo tablets for energy, mood and metabolism support. We topped off our signature oral microbiome-balancing tablets with a perfectly portioned dose of caffeine (10mg), vitamin B12 (6mcg), and L-theanine (2.5mg) to invigorate your system. A feel-good start to the day or whenever you need a pick-me-up. Cinnamon mint chai flavor.

1 Bottle (62 tablets) 

1 Bottle (62 tablets) 

1 Bottle (62 tablets) 

One-Time Purchase

Monthly Delivery

***

Subscribe to

save up to 33%

$18.00

$12.00/month

Save 33%

$18.00

$12.00/month

Save 33%

$18.00

$12.00/month

Save 33%

*** Subscriptions include glass printed bottles of Sleep and Original (1 of each) that hold 62 tablets each along with refills that come in compostable pouches. 

+ 100% Guaranteed - return for full refund if not satisfied
+ Free shipping on all orders over $20

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Plastic free
for the planet

Duo is delivered in apothecary-grade, recyclable glass bottles. Subscription refills come in compostable pouches. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes
end up as trash
each year

Duo Whitening Toothpaste tablets with caffeine and vitamin B12, displayed with packaging.

Plastic free
for the planet

Duo is delivered in apothecary- grade, recyclable glass bottles. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes end up as trash each year

Reviews

4.8
Rated 4.8 out of 5 stars
Based on 318 reviews
318 reviews
  • JR
    JULIEANNE R.
    Verified Buyer
    Reviewing
    Sleep
    I recommend this product
    Rated 5 out of 5 stars
    5 minutes ago
    LOVE duo!

    A clean fresh feeling every time and “sleep“ really helps me do just that! Highly recommend!

  • LC
    Lori C.
    Verified Buyer
    Reviewing
    Immunity
    I recommend this product
    Rated 5 out of 5 stars
    3 days ago
    Surprisingly efficient

    These small tables leave your teeth super clean and I have noticed my teeth are whiter.

  • SP
    Suzann P.
    Verified Buyer
    Reviewing
    Original + 3 Bundle
    I recommend this product
    Rated 5 out of 5 stars
    3 days ago
    Dou original

    Duo works very well. I would buy it again.

  • JC
    Judy C.
    Verified Buyer
    Reviewing
    Original + 3 Bundle
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Love this product!

    I love everything about this product starting with the little glass bottles. I've been trying to get rid of one- time use packaging for all my basic products like shampoos, laundry detergents etc. and the glass bottles along with the compostable refill pouches fit this goal perfectly. I've tried other tooth tablets before but I like the taste of these the best. They're minty but not overpowering. I've also been trying to pay attention to the ingredients in products and wanted to know more about the nano-hydroxyapatite in the product. I emailed the company and got a very detailed response from Mike, one of the co-founders of Duo. I will be a customer for life and am ordering starter sets for my grown children to get them started!