Energy
Toothpaste

Toothpaste tablets to boost energy and
elevate your mood. Infused with caffeine
and vitamin B12.

Learn more

4.9

185 Reviews

Energy
Toothpaste

4.9

Toothpaste tablets to boost energy and

elevate your mood.

Infused with caffeine and vitamin B12.

Learn more

Woman smiling while holding a supplement bottle against a yellow background.

Caffeine + B12:

How It's Absorbed

Your mouth is full of absorbent tissue that delivers the caffeine and vitamin B12 directly into your bloodstream while you brush - no swallowing needed.

Purple circle with a white crescent moon and star icon.

Caffeine is felt almost immediately, no more waiting for coffee to be metabolized. 10mg of caffeine = 1/5 cup of coffee.

Simple moon and star icon on a purple background.

Elevate mood and neurological function with the ideal dose of 6mcg of vitamin B12.

Why Duo?

Better-for-you
toothpaste tablets

Whitens Naturally.

Without peroxides or
chemicals that strip enamel.

Vitamins & Supplements.

Absorbed as you brush for
oral and systemic health.

Travel-Ready.

TSA-compliant and mess-free convenience.

Vegan and Cruelty-Free

Clean ingredients with all-natural flavors for a feel-good routine.

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'

Why Duo?

Better-for-you toothpaste tablets

Whitens Naturally.

Without peroxides or chemicals that strip enamel.

Decreases Sensitivity

Core ingredients, like nHA, insulate nerves without numbing agents.

Hydrating Foam.

Free from SLS and drying agents for healthy balance.

Vitamins & Supplements.

Absorbed as you brush for oral and systemic health.

Travel-Ready

TSA-compliant and mess-free convenience.

Vegan and Cruelty-Free

Clean ingredients with all-natural flavors for a feel-good routine.

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
Smiling person in yellow shirt holding a small bottle, pouring out contents into their hand.

Caffeine + B12:

How It's Absorbed

Your mouth is full of absorbent tissue that delivers the caffeine and vitamin B12 directly into your bloodstream while you brush - no swallowing needed.

Simple moon and star icon on a purple background.

Elevate mood and neurological function with the ideal dose of 6mcg of vitamin B12.

Smiling person in yellow shirt holding a small bottle, pouring out contents into their hand.

Caffeine + B12:

How It's Absorbed

Your mouth is full of absorbent tissue that delivers the caffeine and vitamin B12 directly into your bloodstream while you brush - no swallowing needed.

Purple circle with a white crescent moon and star icon.

Caffeine is felt almost immediately, no more waiting for coffee to be metabolized. (10mg of caffeine = 1/5 cup of coffee)

Simple moon and star icon on a purple background.

Elevate mood and neurological function with the ideal dose of 6mcg of vitamin B12.

How to brush with Duo

1

Chew tablet
to break
down

2

Wet your toothbrush

3

Brush to activate
foam

4

Spit and
smile

Watch explainer with Dr. Stevie Roberts

Hand holding wooden toothbrush with a white pill on bristles, against yellow background.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Best Toothpaste Tablets

"These are fabulous! They aren't powdery when you chew them like some are, and my teeth feel super clean and minty after I'm done. I'm going to keep buying them from now on."

-Erik D.

4.9

194 Reviews

LOVE LOVE LOVE

"I started brushing with Energy to give my mornings a boost before I got to my morning cup of coffee. I now use them for a mid-day refresh and it's become such a lovely (and healthy) ritual. The flavor is refreshing, more foam than any other tablets I've tried, and I can't get over the added benefits of the caffeine & B12."

- Hannah G.

Purchase One-Time or Subscribe

whitens naturally 

without bleaching

nano-hydroxyapatite

for remineralizing teeth

antioxidants

for gum health

caffeine (10mg)

boosts performance

vitamin B12 (6mcg)

elevates mood & energy

vitamins absorbed

directly while brushing

Amber bottle of Duo Whitening Toothpaste tablets with caffeine and vitamin B12.Two jars and two packets of Duo whitening toothpaste tablets in Sleep and Original varieties.

10mg of caffeine || 6mcg of vitamin B12

Energy Whitening

Toothpaste Tablets

4.9

194 Reviews

Get a boost while you brush with Duo tablets for energy, mood and metabolism support. We topped off our signature oral microbiome-balancing tablets with a perfectly portioned dose of caffeine (10mg), vitamin B12 (6mcg), and L-theanine (2.5mg) to invigorate your system. A feel-good start to the day or whenever you need a pick-me-up. Cinnamon mint chai flavor.

1 Bottle (62 tablets) 

1 Bottle (62 tablets) 

1 Bottle (62 tablets) 

One-Time Purchase

Monthly Delivery

***

Subscribe to

save up to 33%

$18.00

$12.00/month

Save 33%

$18.00

$12.00/month

Save 33%

$18.00

$12.00/month

Save 33%

*** Subscriptions include glass printed bottles of Sleep and Original (1 of each) that hold 62 tablets each along with refills that come in compostable pouches. 

+ 100% Guaranteed - return for full refund if not satisfied
+ Free shipping on all orders over $20

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Plastic free
for the planet

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes
end up as trash
each year

Duo Whitening Toothpaste tablets with caffeine and vitamin B12, displayed with packaging.

Plastic free
for the planet

Duo is delivered in apothecary- grade, recyclable glass bottles. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes end up as trash each year

Reviews

4.8
Rated 4.8 out of 5 stars
Based on 362 reviews
362 reviews
  • CA
    Caroline A.
    Verified Buyer
    Reviewing
    Immunity Compostable Refill
    I recommend this product
    Rated 5 out of 5 stars
    3 minutes ago
    Love it!

    I like the taste, the tabs' crunchiness and the clean feeling afterwards. The tabs produce a nice foam to help with the brushing.

  • SD
    Sarah D.
    Verified Buyer
    Reviewing
    Immunity Compostable Refill
    I recommend this product
    Rated 5 out of 5 stars
    10 hours ago
    Fall asleep faster

    I love using the immunity in the morning and the lavender mint(sleep) at night. I had my son try it out he loves the sleep one bc it helps you fall asleep gently. These tablets leave my teeth feeling cleaner, stronger, and with reduced sensitivity.

  • BB
    Blair B.
    Verified Buyer
    Reviewing
    Original Compostable Refill
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Best option we've found!

    I've been purchasing and trying various toothpastes and tooth tablets for the last six months in an effort to find one for my family. My criteria was that it needed to contain nano hydroxyapatite, taste good to my children, and fit in our budget. I've tried four different brands so far and Duo has come out on top. They weren't the cheapest, but my kids wouldn't use the others. They tasted horrible or foamed so much they were rejected! I was also gratified to see the different options of sleep, energy, and immunity. I've tried all so far and have stopped my search.

    I would love to see Duo branch out to other flavors, but the mint flavors are working for us so we won't switch.

  • TP
    Tracy P.
    Verified Buyer
    Reviewing
    Sleep
    I recommend this product
    Rated 5 out of 5 stars
    5 days ago
    These are fabulous!

    I love these everyday and especially for travel. My mouth is so clean!