Halloween-themed whitening toothpaste ad with cobwebs and discount offer.

Learn more about Duo Energy and Immunity

Two bottles of Duo Toothpaste with Halloween-themed text and spider webs.

Learn more about Duo Energy and Immunity

Why Duo?

Better-for-you toothpaste tablets

Whitens Naturally.

Without peroxides or chemicals that strip enamel.

Decreases Sensitivity

Core ingredients, like nHA, insulate nerves without numbing agents.

Hydrating Foam.

Free from SLS and drying agents for healthy balance.

Vitamins & Supplements.

Absorbed as you brush for oral and systemic health.

Travel-Ready

TSA-compliant and mess-free convenience.

Vegan and Cruelty-Free

Clean ingredients with all-natural flavors for a feel-good routine.

Why Duo?

Better-for-you
toothpaste tablets

Whitens Naturally.

Without peroxides or
chemicals that strip enamel.

Hydrating Foam.

Free from SLS and drying
agents for fresher breath.

Vitamins & Supplements.

Absorbed as you brush for
oral and systemic health.

Decreases Sensitivity.

Core ingredients, like nHA, insulate nerves without numbing agents.

Travel-Ready.

TSA-compliant and mess-free convenience.

Vegan and Cruelty-Free

Clean ingredients with all-natural flavors for a feel-good routine.

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
Smiling person in yellow shirt holding a small bottle, pouring out contents into their hand.

Duo Energy:
Caffeine + B12

Your mouth is full of absorbent tissue that delivers the caffeine and vitamin B12 directly into your bloodstream while you brush - no swallowing needed.

Purple circle with a white crescent moon and star icon.

Caffeine is felt almost immediately- no more waiting for coffee to be metabolized. 10mg of caffeine = 1/5 cup of coffee.

Simple moon and star icon on a purple background.

Elevate mood and neurological function with the ideal dose of 6mcg of vitamin B12.

Duo Immunity:
Vitamins D3 + B12

Your mouth has thousands of capillaries that absorb nutrients directly into the bloodstream while you brush - no swallowing needed.

Keep your immune system strong in all seasons with highly bioavailable vitamin D3.

Elevate mood and neurological function with the ideal dose of vitamin B12.

A woman with a towel around her shoulders brushing her teeth, smiling.

Trusted by the industry

Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'
Two hands forming a heart shape against a colorful sunset background.'Logo with the letters RDH in black font.'Two hands forming a heart shape against a colorful sunset background.'Dental Economics magazine cover featuring industry-related content.''MyDental Advocate logo with a tooth graphic.'

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Best Toothpaste Tablets

"These are fabulous! They aren't powdery when you chew them like some are, and my teeth feel super clean and minty after I'm done. I'm going to keep buying them from now on."

-Erik D.

4.9

196 Reviews

LOVE LOVE LOVE

"I started brushing with Energy to give my mornings a boost before I got to my morning cup of coffee. I now use them for a mid-day refresh and it's become such a lovely (and healthy) ritual. The flavor is refreshing, more foam than any other tablets I've tried, and I can't get over the added benefits of the caffeine & B12."

- Hannah G.

Halloween Bundle - 40% Off

2 bottles + 2 refills pouches = 4 month supply (248 tablets)

whitens naturally 

without bleaching

nano-hydroxyapatite

for remineralizing teeth

vitamin D3 (30mcg)

to bolster defenses

caffeine (10mg)

boosts performance

vitamin B12 (6mcg)

elevates mood

vitamins absorbed

directly while brushing

Duo toothpaste Halloween bundle featuring Immunity and Energy bottles with refills.Two jars and two packets of Duo whitening toothpaste tablets in Sleep and Original varieties.

Immunity/Energy + 2 Bundle

4.9

194 Reviews

Immunity:

30mcg of vitamin D3 || 6mcg of vitamin B12

Energy:

10mg of caffeine || 6mcg of vitamin B12

Duo Energy toothpaste provides a boost to your morning with a kick of caffeine (10mg) + vitamin B12 (6mcg), getting you ready to take on the day with confidence. And with Duo Immunity you will get 2x the daily recommended value of vitamin D (30mcg) and B12 (6mcg). That means stronger bones, better cognition, and a tougher immune system.

10mg of caffeine || 6mcg of vitamin B12

Get a boost while you brush with Duo tablets for energy, mood and metabolism support. We topped off our signature oral microbiome-balancing tablets with a perfectly portioned dose of caffeine (10mg), vitamin B12 (6mcg), and L-theanine (2.5mg) to invigorate your system. A feel-good start to the day or whenever you need a pick-me-up. 

+ 100% Guaranteed - return for full refund if not satisfied
+ Free shipping on all orders over $20

How to brush with Duo

1

Chew tablet to break down

2

Wet your toothbrush

3

Brush to activate foam

4

Spit and smile

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

VEGAN

NON-TOXIC

SLS-FREE

DENTIST-CREATED

CRUELTY-FREE

FLUORIDE-FREE

PLASTIC-FREE

MADE IN U.S.

Plastic free
for the planet

Duo is delivered in apothecary-grade, recyclable glass bottles. Subscription refills come in compostable pouches. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes
end up as trash
each year

Duo Whitening Toothpaste tablets with caffeine and vitamin B12, displayed with packaging.

Plastic free
for the planet

Duo is delivered in apothecary- grade, recyclable glass bottles. It’s the future of toothpaste and better for all of us.

500
years

to break down a
single plastic
toothpaste tube

1.5

billion

plastic tubes end up as trash each year

Reviews

4.9
Rated 4.9 out of 5 stars
Based on 199 reviews
199 reviews
  • JS
    Janice S.
    Verified Buyer
    Sleep
    Reviewing
    Sleep
    I recommend this product
    Rated 5 out of 5 stars
    3 minutes ago
    Love this!

    I track my sleep patterns with my Oura ring, so I know exactly when I fall asleep and how "good" my sleep is. Since I started using Duo, I fall asleep quickly and easily, within minutes of brushing my teeth. And I have a great night's sleep. So happy to have found a product that does what it says it will. And it's a lovely taste experience when brushing, too!

  • CS
    Cathy S.
    Verified Buyer
    Sleep
    Reviewing
    Sleep
    I recommend this product
    Rated 5 out of 5 stars
    18 hours ago
    Sleep Duo

    I was skeptical but brushing with Sleep about 30 minutes before bedtime is enough to make me drowsy and able to drift off. Thank you Duo. ❤️

  • R
    Rhonda
    Sleep
    Reviewing
    Sleep
    I recommend this product
    Rated 5 out of 5 stars
    3 days ago
    5 Stars

    I like these toothpaste tablets. Have never had anything like this before. Leaves my mouth minty fresh

  • D
    Diana
    Sleep
    Reviewing
    Sleep
    I recommend this product
    Rated 5 out of 5 stars
    5 days ago
    5 Stars

    Great product to help sleep.

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